human microrna (mirna) microarray v1.0 (Agilent technologies)
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Human Microrna (Mirna) Microarray V1.0, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+microrna+microarray+v1%2E0/pmc07328332-182-8-13
Average 90 stars, based on 1 article reviews
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1) Product Images from "A Network of Sputum MicroRNAs Is Associated with Neutrophilic Airway Inflammation in Asthma"
Article Title: A Network of Sputum MicroRNAs Is Associated with Neutrophilic Airway Inflammation in Asthma
Journal: American Journal of Respiratory and Critical Care Medicine
doi: 10.1164/rccm.201912-2360OC
Figure Legend Snippet: Weighted gene correlation network analysis of sputum microRNA expression and asthma features (n = 78 samples). Using expressed microRNAs (n = 221) in the sputum, six modules were identified. These modules had correlations with multiple demographic, clinical, physiologic, and sputum characteristics. Positive correlations are red, and negative correlations are blue. The microRNAs in the blue (nely) module were positively associated with age, asthma duration, hospitalizations in the previous year, bronchodilator response, and neutrophil and lymphocyte cell counts in the sputum; and negatively correlated with asthma quality of life (AQLQ), FEV1% predicted, and FVC% predicted at baseline. Values are correlation coefficient (nominal P value). BDR = bronchodilator response; Eos = eosinophil; FeNO = fractional exhaled nitric oxide; Lymph = lymphocyte; Mac = macrophage; miRNA = microRNA; Neu = neutrophil.
Techniques Used: Expressing
Figure Legend Snippet: Weighted gene correlation network analysis of microRNA (miR) and mRNA expression in matched sputum samples (n = 21). Weighted gene correlation network analysis heatmap of the correlation between genes expressed in the sputum (n = 16,966). This analysis identified 32 gene modules correlated with the 12 microRNAs included in the nely microRNA module in paired mRNA and microRNA samples obtained from the same individuals. Positive correlations are red, and negative correlations are blue. Two modules had the most positive and negative correlations. The lightcyan mRNA module had positive correlations with 10 nely module microRNAs, and the turquoise module had negative correlations with 8 nely module microRNAs. Gene enrichment analysis of the lightcyan mRNA module revealed enrichment for TLR (Toll-like receptor) pathways and T-helper cell type 17 pathways, and the turquoise mRNA module was enriched for the unfolded protein response (UPR). These putative biological functions for the two modules are highlighted in the module. Values are correlation coefficient (nominal P value).
Techniques Used: Expressing
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